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OS24 - Evolving Approaches to Patient Care (ID 29)
- Event: e-Health 2017 Virtual Meeting
- Type: Oral Session
- Track: Clinical and Executive
- Presentations: 1
- Coordinates: 6/07/2017, 10:30 AM - 12:00 PM, Room 201CD
OS24.02 - The Last Clinical Mile of Precision Medicine – Challenges at POC (ID 140)
Purpose/Objectives: Medical history is notable for game-changing breakthroughs. Germ-destroying sterilization. Miracle drugs like penicillin. Lifesaving organ transplants. Precision medicine is equally revolutionary. It signals a significant shift from generalized medicine the traditional one-size-fits-all and trial-by-error approachto personalized medicine with testing and treatments tailored for individuals. But barriers exist. The most significant? The gap between genomic information and its timely, meaningful application at the point of care. Today, the science of genomics occurs in labs (blood, tissue testing), research facilities (omics, sequencing), pharmaceutical companies (biomarkers for specific drug efficacy) and clinical trial programs. But, its not accessible in actionable, meaningful clinical terms; nor is it structured and harmonized with the clinical context of the patient. And it is not available in the current workflow of the clinician.
Methodology/Approach: Up until now, medical knowledge and therapies were tested on broad populations and prescribed using statistical averages. And that meant they would work for some patients but not for many others. The potential result? Diagnosis and treatment delays or inaccuracies that might have catastrophic impact. Precision medicine factors genes, environment, lifestyle factors and family history into all clinical decision-making for earlier, accurate diagnoses, and more effective treatment and prevention. In other words, precision medicine overcomes the limitations of traditional health care by taking individualized factors into consideration. Clinicians are able to analyze the potential diagnosis, match and tailor the right treatment, and review the efficiency of current protocols.
Finding/Results: Here are just a few reasons why precision medicine is taking center stage in health care today: a. *Patients 9 out of 10 causes of death are influenced by genetics. b. Providers 30% reduced ED vists by applying molecular profiling treatment strategy. c. Payers - $25 billion annual spending on genetic tests by 2021. d. Pharma - $7.5 billion will be the size of the pharmacogenomics market by 2017. e. Government* - $215 million: President Obamas precision medicine initiative investment.
Conclusion/Implication/Recommendations: As physicians, we want to offer the best possible care plan for every patient, every time. When treating conditions, such as tumors or inherited diseases, we want tools that help us incorporate the many factors that affect each individual. This is where precision medicine comes in. As defined by the National Institutes of Health (NIH), precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment and lifestyle for each person. The good news for patients today is that there is an increasing number of genetic diagnoses, while at the same time, the costs to sequence a human genome are dropping. We are in a better position than ever before to tailor medicine to the individual. For the first time, were seeing some alignment on the importance of precision medicine. All of these stakeholders are coming together to help realize the promise of genomic knowledge. When delivered at the point of care, precision medicine will have the greatest impact.
140 Character Summary: Precision medicine is revolutionary for healthcare and is taking center stage with patients, providers, payers, pharma, and government.